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To evaluate and identify factors predictive for morbidity after radical nephrectomy in patients with metastatic renal cell carcinoma mRCC. Postoperative complications were characterised using a modified version of the Clavien-Dindo classification system. Patient and disease characteristics, including a ly validated MSKCC risk-stratification system using calcium, haemoglobin Hb , lactate dehydrogenase, and Karnofsky Performance Status KPS , were evaluated as predictors of postoperative complications using univariate and multivariable logistic regression models. The area under the receiver operating characteristic curve AUC was calculated for each model to assess predictive accuracy and corrected for overfit using fold cross validation.
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